Determination of pefloxacin concentration in mesenteric lymph nodes by high-performance chromatography

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Determination of pefloxacin concentration in mesenteric lymph nodes by high-performance chromatography.

Ten patients who had undergone laparotomies for different abdominal pathological conditions were studied to determine the levels of pefloxacin in mesenteric lymph nodes. Each patient was given 400 mg of oral pefloxacin every 12 h for the 3 days prior to surgery. Drug levels in tissue were determined by high-pressure liquid chromatography (reverse phase); the mean +/- standard deviation was 17.1...

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ژورنال

عنوان ژورنال: Antimicrobial Agents and Chemotherapy

سال: 1994

ISSN: 0066-4804,1098-6596

DOI: 10.1128/aac.38.3.632